The THS4531ID is a low-power fully-differential Operational Amplifier with input common-mode range below the negative rail and rail-to-rail output. The device is designed for low-power data acquisition systems and high density applications where power consumption and dissipation is critical. The device features accurate output common-mode control that allows for DC coupling when driving analog-to-digital converters (ADCs). This control, coupled with the input common-mode range below the negative rail and rail-to-rail output, allows for easy interface from single-ended ground-referenced signal sources to successive-approximation registers (SARs) and delta-sigma (ΔΣ) ADCs using only single-supply 2.5 to 5V power. The THS4531 is also a valuable tool for general-purpose, low-power differential signal conditioning applications.