The AD8253ARMZ is an Instrumentation Amplifier with digitally programmable gains that has gigaohm (GR) input impedance, low output noise and low distortion, making it suitable for interfacing with sensors and driving high sample rate analogue-to-digital converters (ADCs). In addition to its wide input common voltage range, it boasts a high common-mode rejection of 100dB at G=1000 from DC to 20kHz. The combination of precision DC performance coupled with high speed capabilities makes this an excellent candidate for data acquisition. Furthermore, this monolithic solution simplifies design and manufacturing and boosts performance of instrumentation by maintaining a tight match of internal resistors and amplifiers.