The AD8221ARMZ is a Precision Instrumentation Amplifier that delivers the industry's highest CMRR over frequency in its class. The CMRR of instrumentation amplifier on the market today falls off at 200Hz. In contrast, this maintains a minimum CMRR of 80dB to 10kHz for all grades at G=1. High CMRR over frequency allows this to reject wideband interference and line harmonics, greatly simplifying filter requirements. Possible applications include precision data acquisition, biomedical analysis and aerospace instrumentation. A single resistor sets the gain from 1 to 1000. This operates on both single and dual supplies and is well suited for applications where ±10V input voltages are encountered.