The AD8220BRMZ is a single-supply JFET input Instrumentation Amplifier designed to meet the needs of high performance, portable instrumentation, the AD8220 has a minimum common-mode rejection ratio (CMRR) of 86dB at DC and a minimum CMRR of 80dB at 5kHz for G=1. Maximum input bias current is 10pA and typically remains below 300pA over the entire industrial temperature range. Despite the JFET inputs, the AD8220 typically has a noise corner of only 10Hz. With the proliferation of mixed-signal processing, the number of power supplies required in each system has grown. The AD8220 is designed to alleviate this problem. The AD8220 can operate on a ±18V dual supply, as well as on a single +5V supply. Its rail-to-rail output stage maximizes dynamic range on the low voltage supplies common in portable applications. Its ability to run on a single 5V supply eliminates the need to use higher voltage, dual supplies.